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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EOMES
All Species:
15.76
Human Site:
S216
Identified Species:
28.89
UniProt:
O95936
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95936
NP_005433.2
686
72732
S216
G
P
G
A
G
A
G
S
G
A
G
G
S
S
G
Chimpanzee
Pan troglodytes
XP_001165803
690
73333
S220
V
P
G
A
G
A
G
S
G
A
G
G
S
S
G
Rhesus Macaque
Macaca mulatta
XP_001093085
737
80029
S248
F
G
P
G
G
S
G
S
G
A
G
G
S
S
G
Dog
Lupus familis
XP_850738
688
72729
S218
G
P
G
A
G
A
S
S
G
A
G
G
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
O54839
707
74783
S218
G
P
A
A
G
S
G
S
G
A
G
S
S
G
G
Rat
Rattus norvegicus
XP_001061749
663
70857
V203
P
G
G
V
P
A
A
V
C
P
P
A
R
W
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514679
386
42515
Chicken
Gallus gallus
XP_426003
399
44936
Frog
Xenopus laevis
P79944
692
75925
F203
S
M
L
P
P
A
G
F
S
P
P
V
C
P
S
Zebra Danio
Brachydanio rerio
NP_571754
661
71990
P202
S
L
S
S
M
P
I
P
G
S
G
S
A
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
H277
G
L
R
F
P
P
H
H
P
G
A
H
P
H
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
Sea Urchin
Strong. purpuratus
XP_791266
946
105128
S317
G
G
S
L
G
P
P
S
S
H
S
F
G
H
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
80
96.5
N.A.
87.5
81.6
N.A.
25.6
52.4
62.1
57.5
N.A.
22.9
N.A.
24.7
23.6
Protein Similarity:
100
99.1
82.9
96.9
N.A.
89.3
83.9
N.A.
33.5
54.5
70.5
68.9
N.A.
35.2
N.A.
34.9
37.9
P-Site Identity:
100
93.3
66.6
80
N.A.
73.3
13.3
N.A.
0
0
13.3
13.3
N.A.
6.6
N.A.
0
20
P-Site Similarity:
100
93.3
73.3
80
N.A.
80
13.3
N.A.
0
0
13.3
40
N.A.
6.6
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
31
0
39
8
0
0
39
8
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
39
24
31
8
47
0
39
0
47
8
47
31
16
16
39
% G
% His:
0
0
0
0
0
0
8
8
0
8
0
8
0
16
8
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
16
8
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
31
8
8
24
24
8
8
8
16
16
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% R
% Ser:
16
0
16
8
0
16
8
47
16
8
8
16
31
24
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _